Simultaneous T₁, T₂, and T_1ρ mapping of the myocardium using cardiac MR fingerprinting with a deep image prior reconstruction.

ABSTRACT:

Purpose

To develop a cardiac MR fingerprinting (cMRF) approach using deep image prior reconstruction (DIP) to simultaneously map T₁, T₂, and T_1ρ, and assess T_1ρ in healthy subjects and patients with areas of enhancement on late gadolinium enhancement.

Methods

A 2D electrocardiogram-triggered cMRF sequence was developed to measure T₁, T₂, and T_1ρ simultaneously. DIP reconstruction was evaluated for noise and artifact reduction compared to a low-rank reconstruction. Measurements were assessed in simulation and phantom for accuracy. T_1ρ-cMRF maps were generated in 10 healthy subjects and six patients under evaluation for cardiomyopathy, myocarditis, and amyloidosis receiving gadolinium-based

SUBMITTER: Kaplan S 

PROVIDER: S-EPMC12309879 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature