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ABSTRACT: Purpose
To develop a 3D MRI-thermometry technique for transcranial MR-guided focused ultrasound (MRgFUS).Methods
A stack of retraced in-out (RIO) spirals was incorporated into a 3D, RF-spoiled, gradient recalled echo (GRE) sequence with a minimized energy deblurring strategy. Bloch simulations examined isochromat precession during RIO readout under temperature profiles matching those encountered during transcranial MRgFUS and measured the resulting effects on observed peak temperatures and FWHM of the heating patterns. The sequence then monitored temperatures in a phantom undergoing insonation from an MRgFUS device. Finally, the sequence monitored temperatures, without insonation, in four patients immediately after MRgFUS thalamotomy. For comparison, temperatures were also
SUBMITTER: Allen SP
PROVIDER: S-EPMC12309881 | biostudies-literature | 2025 Oct
REPOSITORIES: biostudies-literature