Metabolome trajectories in male and female athletes.

ABSTRACT:

Background

Integrating metabolomics in sports science provides valuable insights into the biochemistry of bodies during physical activity. However, due to their invasiveness, traditional blood sampling methods present challenges in sports settings. The study investigated sex-specific metabolic responses, addressing a significant gap in exercise research, where female participation remains underrepresented.

Methods

To address this, we explored volumetrically accurate microsampling as a dried blood spot (DBS) technique for assessing metabolomic changes in response to acute exercise in more than 130 participants. This study employed a targeted quantitative approach using isotopically labeled internal standards to measure over 100 metabolites with DBS, providing accurate and tra

SUBMITTER: Schoeny H 

PROVIDER: S-EPMC12309969 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature