Development of a core outcome set for trials for management of oral submucous fibrosis (OSFCOS): A consensus study protocol.

ABSTRACT:

Background

The effectiveness of oral submucous fibrosis (OSF) treatment is currently assessed with a broad range of clinical outcome measures. This heterogeneity complicates study comparison, synthesis of results, and evidence-based clinical practice guideline development. A core outcome set (COS) is a set of agreed, standardized outcomes that will be measured and reported across all clinical trials for a particular condition.

Objective

Our aim is to create a COS (OSFCOS) for efficacy trials that look at the management OSF.

Methods

An initial list of the potentially relevant outcomes will be drawn by a systematic review of randomized controlled trials focused on OSF treatment. An e-Delphi process will be done to obtain agreement among important stakeholders. The stake

SUBMITTER: Gondivkar SM 

PROVIDER: S-EPMC12309984 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature