Harnessing immunotherapy: cancer vaccines as novel therapeutic strategies for brain tumor.

ABSTRACT: Cancer vaccines have emerged as a pivotal area of research in oncology, demonstrating significant promise in harnessing the immune system to combat cancer. Recent advancements in antigen identification and sequencing techniques have catalyzed the development of cancer vaccines whose goal is to elicit robust humoral and cellular immune responses against cancer cells. Despite their potential, most cancer vaccines are still in the experimental phase, primarily due to challenges associated with tumor-induced immune suppression. This article explores the role of cancer vaccines in brain cancer, glioblastoma, by providing a granular analysis of clinical trial results and mechanisms of resistance alongside a comparative assessment. These vaccines aim to navigate the immunosuppressive tumor microe

SUBMITTER: Kiel K 

PROVIDER: S-EPMC12310467 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature