Clinical characteristics of fatal cases of hand, foot and mouth disease in children.

ABSTRACT:

Background

Hand, foot and mouth disease (HFMD) is a common infectious disease that continues to pose a serious threat to children. The purpose of this study was to analyze the clinical characteristics and causes of death of mortality among children with fatal HFMD.

Methods

Clinical data from children who had HFMD and died in the pediatric intensive care units of Henan Children's Hospital from January 2014 to December 2019 were retrospectively analyzed.

Results

Thirty-one fatal cases were identified (19 males, 12 females), aged 9-47 months, all without underlying disease. Mortality was highest among children aged 12-36 months. A declining trend in deaths was observed from 2014 to 2019. The median duration of disease was 4.5 days. Common clinical manifestations included

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12310577 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature