The Mycobacterium tuberculosis ESAT-6 homologue in Listeria monocytogenes is dispensable for growth in vitro and in vivo.

ABSTRACT: ESAT-6 is a virulence determinant in Mycobacterium tuberculosis and a member of a conserved group of proteins in a variety of other bacteria. A targeted deletion of the homologous gene in Listeria was generated, and in contrast to that observed for mycobacteria, this locus was not required for Listeria virulence.

SUBMITTER: Way SS 

PROVIDER: S-EPMC1231089 | biostudies-literature | 2005 Sep

REPOSITORIES: biostudies-literature