Spiking dynamics of individual neurons reflect changes in the structure and function of neuronal networks.

ABSTRACT: Brain networks exhibit diverse topological structures to adapt and support brain functions. The changes in neuronal network architecture can lead to alterations in neuronal spiking activity, yet how individual neuronal behavior reflects network structure remains unexplored. Therefore, mathematical tools to decode and infer neuronal network structure and role from spiking behavior need to be developed to relate the neuronal firing activity with topology and goal of underlying network. Toward this end, we perform a comprehensive multifractal analysis of the neuronal interspike intervals to characterize their non-linear, non-stationary and non-Markovian dynamics. We explore the relationship of neuronal network connectivity with the multifractal spiking pattern and show that such a measure is

SUBMITTER: Yang R 

PROVIDER: S-EPMC12310945 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature