A Methodological and Survival Comparison of NCDB and SEER Database for Colon Cancer Research.

ABSTRACT:

Background

The National Cancer Database (NCDB) and Surveillance, Epidemiology, and End Results (SEER) database are widely used in colon cancer research, particularly for analyzing overall survival (OS) rates. However, differences in demographics, treatment patterns, and survival outcomes across colon cancer stages and locations between these databases remain incompletely understood. Addressing these disparities is crucial for researchers when selecting the most appropriate registry for survival analysis.

Objectives

This study aims to systematically compare patient characteristics, oncologic outcomes, and OS rates between NCDB and SEER across various tumor locations and disease stages in colon cancer.

Methods

We analyzed patients undergoing surgery for Stages I-IV prim

SUBMITTER: Erkaya M 

PROVIDER: S-EPMC12311401 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature