R0 Resection Rates in Minimally Invasive Versus Open Pelvic Exenteration for Colorectal Malignancies: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background and objectives

Pelvic exenteration is a curative option for select patients with locally invasive or recurrent colorectal cancer. Achieving clear margins (R0 resection) is critical for optimal oncological outcomes and quality of life. Minimally invasive surgery (MIS), including laparoscopic and robotic approaches, offers advantages in visualisation and precision, but its feasibility is debated given data limitations. This meta-analysis compares outcomes of MIS with open pelvic exenteration for colorectal cancer.

Methods

A systematic review and meta-analysis were conducted with studies comparing MIS to open approaches for pelvic exenteration in colorectal cancer included. The primary outcome was R0 resection rate, with secondary outcomes encompassing operative, pos

SUBMITTER: Cheng E 

PROVIDER: S-EPMC12311406 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature