Sustainable Synthesis of Trimethylolpropane, a Biobased Polyol from Renewable Resources by an Integrated Process of Biotechnology and Chemical Reactions.

ABSTRACT: Trimethylolpropane (TMP) is an important industrial chemical used to produce various value-added chemicals and polymers. In this study, both biobased butyraldehyde and formaldehyde were produced by the incomplete oxidation of bio-1-butanol and biomethanol, respectively, and were then used to produce a biobased TMP. High selective incomplete oxidation of primary alcohol to aldehyde is a challenging process minimizing the corresponding carboxylic acid, a complete oxidation product. DSM 2343 was found to have high activity and selectivity for the oxidation of butanol to butyraldehyde by whole-cell biotransformation. A pH 5 and greater than 15 g/L of 1-butanol are preferable conditions for butyraldehyde accumulation. In a 1 L bioreactor experiment, 18 g/L of bio-1-butanol was oxidized to 13 g/

SUBMITTER: Sayed M 

PROVIDER: S-EPMC12311669 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature