PEDOT:PSS-Loaded Gelatin Cryogels for Electrically Controlled Drug Release.

ABSTRACT: Conductive cryogel is a new form of biomaterial that provides additional electrical properties, expanding its applications in biomedical engineering, particularly in tissue regeneration, such as neural and muscle tissues, and in drug-delivery systems. In this study, the gelatin cryogels (GCs) incorporating the conductive polymer PEDOT:PSS (PGC) at an optimal ratio (PGC2) could achieve suitable conductivity as an electrically responsive scaffold applied for controlled drug release. The characterization results demonstrated that PGC2 exhibited a well-defined porous structure (90-190 μm), a favorable water uptake capacity (2738.4%), degradability (26.1% degradation after 24 h), and reversible deformability upon compression, demonstrating its suitability for minimally invasive procedures via i

SUBMITTER: Chen HA 

PROVIDER: S-EPMC12311670 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature