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Potentiometric Detection of Calcium Ions Using an Organic Electrochemical Transistor.


ABSTRACT: Excreted biological fluids represent a matrix rich in useful biomarkers that can be correlated with a vast number of medical conditions and physiological processes, for both diagnostic and therapeutic purposes. Among the plethora of medically relevant analytes, the calcium ion is a target of prime interest, as it is present in many biofluids such as saliva, sweat, and wound exudate. Its concentration can be associated with a variety of afflictions, such as osteoporosis, periodontal diseases, kidney stone formation, parathyroid gland activity, and impaired wound healing. In this work, we present a novel device architecture for the potentiostatic, reference electrode-free detection of calcium, renovating the original organic electrochemical transistor (OECT) model by Wrighton. The sensing ev

SUBMITTER: Arcangeli D 

PROVIDER: S-EPMC12311683 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature