Retinal parameter analysis and diagnostic potentail exploration in familial exudative vitreoretinopathy using ultra-widefield fundus photography.

ABSTRACT:

Background

Familial Exudative Vitreoretinopathy (FEVR) is a monogenic disorder causing retinal vascular impairment, often underdiagnosed due to its variable presentation and reliance on invasive methods like fundus fluorescein angiography (FFA). Through the utilization of non-invasive ultra-widefield fundus photography (UWFFP), this research explored both the diagnostic potential of integrated retinal parameters for the detection of FEVR, and their characteristic changes during the early stage progression.

Methods

Retinal parameters were systematically extracted and quantified from UWFFP of 114 FEVR patients and 114 matched controls using the EVision AI cloud platform. Comparative statistical analyses were performed to identify significant intergroup differences between FEVR

SUBMITTER: Li J 

PROVIDER: S-EPMC12312263 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature