Opioid Analgesia Following Pediatric Adenotonsillectomy: A Randomized Clinical Trial.

ABSTRACT:

Objective

To compare the safety and efficacy of nonopioid versus opioid pain management following adenotonsillectomy (AT) among pediatric patients.

Study design

An open-label randomized controlled trial.

Setting

Tertiary care children's hospital.

Methods

Patients aged 3 to 17 years undergoing AT were eligible. Participants were randomly assigned to receive either acetaminophen and ibuprofen (nonopioid group) or acetaminophen, ibuprofen, and oxycodone (opioid group). Pain scores and prevalence of emergency department (ED) visits, hospital readmission, and posttonsillectomy hemorrhage (PTH) were compared between groups.

Results

From January 2019 to March 2020, 267 patients were enrolled and randomly assigned; 144 completed a postoperative pain diary. Of th

SUBMITTER: Whelan RL 

PROVIDER: S-EPMC12312295 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature