Elective Neck Dissection in cT1-4 N0M0 Head and Neck Spindle Cell Carcinoma.

ABSTRACT:

Objective

To investigate the survival benefit of elective neck dissection (END) over neck observation in surgically resected cT1-4 N0M0 head and neck spindle cell carcinoma (HNSpCC).

Study design

Retrospective cohort study.

Setting

The 2006 to 2018 hospital-based National Cancer Database (NCDB).

Methods

Patients with surgically resected cT1-4 N0M0 HNSpCC were selected. Linear, binary logistic, Kaplan-Meier, and Cox proportional hazards regression models were implemented.

Results

Of 815 patients satisfying inclusion criteria, a high proportion were male (72.4%) and white (86.0%) with disease of the larynx (43.8%) classified as high grade (87.7%) and cT1-2 (74.8%). In total, 235 (28.8%) patients underwent END. END utilization between 2006 and 2018 increase

SUBMITTER: Kaki PC 

PROVIDER: S-EPMC12312297 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature