Anxiety and depression symptoms mediate the impact of neuroticism on insomnia in adults with epilepsy: a cross-sectional study.

ABSTRACT:

Objective

Comorbid insomnia is a common global occurrence among patients with epilepsy (PWE). Neuroticism could be a significant underlying factor for insomnia in this population. This study aimed to explore whether and how neuroticism, anxiety, and depressive symptoms interact and impact insomnia in PWE.

Methods

We recruited a continuous cohort of adult PWE. Demographic, clinical data, and information on neuroticism, anxiety, depression, and insomnia were collected. Assessments were conducted using the Eysenck Personality Questionnaire-Revised, Short Scale for Chinese (EPQ-RSC), Generalized Anxiety Disorder-7 (GAD-7), Neurological Disorders Depression Inventory for Epilepsy (NDDI-E), and Insomnia Severity Index (ISI). Process mediation analysis were employed to Investigate

SUBMITTER: Hu P 

PROVIDER: S-EPMC12312321 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature