Global, regional, and national burden of endocarditis, 1990-2021: a systematic analysis of the GBD 2021 study.

ABSTRACT:

Background

Endocarditis is a serious cardiovascular infection associated with high mortality and disability. Its global epidemiological patterns and long-term trends have not been comprehensively characterized.

Methods

Data from the Global Burden of Disease (GBD) Study 1990-2021 were used to evaluate the prevalence, incidence, disability-adjusted life years (DALYs), and Deaths of endocarditis across 204 countries and territories. Temporal trends were analyzed using percentage change and estimated annual percentage change (EAPC), stratified by Socio-demographic Index (SDI), region, age, and sex.

Results

Between 1990 and 2021, the absolute number of endocarditis cases increased: prevalence by 14%, incidence by 34%, DALYs by 26%, and Deaths by 29%. Conversely, age-standa

SUBMITTER: Feng J 

PROVIDER: S-EPMC12312326 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature