Flow cytometry for screening and prioritisation of urine samples: a retrospective comparison with culture.

ABSTRACT:

Background

Efficient urinary tract infection (UTI) diagnostics require reliable methods to rapidly exclude negative samples while accurately identifying positive cases. Automated urine flow cytometry (UFC) offers a promising approach to streamline laboratory workflows by reducing unnecessary cultures and providing early bacterial classification. This study evaluated the performance of a UFC-based screening method compared to conventional urine culture.

Methods

4005 urine samples were analysed using UFC (Sysmex UF-5000) and compared to culture results. Receiver operating characteristic (ROC) curve analyses assessed method agreement across different patient subpopulations. Predictive values were calculated for the total population and the ten different subpopulations at differ

SUBMITTER: Sender V 

PROVIDER: S-EPMC12312330 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature