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The association of ultra-processed food intake on age-related muscle conditions: a systematic review and dose-response meta-analysis with meta-regression.


ABSTRACT:

Objectives

Chronic excessive intake of ultra-processed foods (UPFs) has been linked to various metabolic conditions; however, its impact on skeletal muscle mass and function in older adults remains unclear. Therefore, we conducted this study to examine the association between UPF intake and age-related muscle outcomes, including frailty, sarcopenia, low muscle mass (LMM), and/or low muscle strength (LMS).

Methods

A systematic search was conducted in ISI Web of Science, LILACS, PubMed/MEDLINE, and Scopus without restrictions up to November 1, 2024. Relative risks (RRs) and 95% confidence intervals (CIs) were pooled using a random-effects model. Study quality and the presence of publication bias were assessed using the Newcastle-Ottawa Scale, Egger's regression asymmetry test,

SUBMITTER: Hojjati Kermani MA 

PROVIDER: S-EPMC12312346 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature