Three-Dimensional Choroidal Vessel Analysis in Asymmetric Bilateral Age-Related Macular Degeneration: A Comparison of Active Neovascular AMD and Dry AMD Fellow Eyes.

ABSTRACT:

Purpose

To assess choroidal vasculature in bilateral age-related macular degeneration (AMD) patients, with neovascular AMD in one eye and dry AMD in the other, using an innovative three-dimensional (3D) algorithm.

Methods

This retrospective cross-sectional study included 30 patients with asymmetric bilateral AMD. All patients underwent clinical exams and swept-source optical coherence tomography using PlexElite-9000 (Carl Zeiss Meditec, Dublin, CA) scans centered on the fovea. The 3D choroidal vasculature was segmented using our validated deep learning algorithm. These 3D maps were divided into five sectors, with the three largest vessels in each sector selected for mean choroidal vessel diameter and inter-vessel distance (IVD) measurements. Volumetric choroidal thickness (C

SUBMITTER: Sadeghi E 

PROVIDER: S-EPMC12312765 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature