Maternal psychophysiology profiles: associations with prenatal opioid use, maternal emotion dysregulation, and newborn neurobehavior.

ABSTRACT:

Background

Opioid use among pregnant women has more than quadrupled over the past 20 years; however, comorbid risk factors such as emotion dysregulation confound the developmental consequences of prenatal opioid use. Maternal respiratory sinus arrhythmia (RSA) may help to disentangle the comorbid risk factors of prenatal emotion dysregulation and substance use and isolate their consequences on newborn neurobehavior.

Methods

We examined maternal RSA in response to a mild, infant-related stress task in pregnant people (N = 192; 30 on medications for opioid use disorder) recruited from hospitals and a specialty prenatal clinic for substance use disorder.

Results

Three latent profiles emerged based on maternal RSA reactivity. Mothers with RSA increasing (Profile 3; more n

SUBMITTER: Maylott SE 

PROVIDER: S-EPMC12312871 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature