Safety of median nerve electrical stimulation in disorders of consciousness: A systematic review and meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Median nerve electrical stimulation (MNS) is a noninvasive treatment technique that can improve the brain functional activity of patients with disorders of consciousness (DoC) and promote their awakening. However, there is no research on whether MNS increases the incidence and severity of DoC complications. In this study, we evaluated the safety of MNS for the treatment of DoC.

Methods

We searched relevant studies in PubMed, Cochrane, Web of Science (Medline), and Chinese databases, including CNKI, VIP, and WanFang Databases. For dichotomous outcomes, the pooled risk ratio (RR) with its 95% confidence interval (CI) was used as the effect estimate. We applied a fixed-effects or random-effects model to test the robustness of the forecast. A funnel plot was used to t

SUBMITTER: Gu C 

PROVIDER: S-EPMC12312889 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature