Nonlinear relationship between body roundness index and prevalence of rheumatoid arthritis in American adults.

ABSTRACT:

Background

The Body Roundness Index (BRI) assesses obesity and fat distribution, yet its correlation with rheumatoid arthritis (RA) is unclear. This study investigated the association between BRI and RA prevalence.

Methods

Using NHANES data from 2011-2018, we conducted a cross-sectional analysis. Logistic regression assessed the BRI-RA relationship, adjusting for various variables. Restricted cubic splines and threshold saturation analysis explored nonlinear associations. Subgroup and sensitivity analyses confirmed the robustness of findings.

Results

A total of 19,875 participants were included in the cross-sectional study. Participants with RA had significantly higher BRI compared with non-RA participants. Logistic regression showed that BRI was positively associated

SUBMITTER: Cao X 

PROVIDER: S-EPMC12313493 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature