Acupoint stimulation methods for premature ovarian insufficiency: a systematic review and network meta-analysis of randomized controlled trials.

ABSTRACT:

Objective

The aims of this study were to evaluate and rank the efficacy of different acupoint stimulation (AS) therapies in the treatment of premature ovarian insufficiency (POI) by network meta-analysis (NMA) and to explore the optimal AS regimen for improving sex hormone levels and clinical symptoms.

Methods

Randomized controlled trials (RCTs) in English and Chinese up to November 2024 were searched in eight databases, including the Cochrane Library, PubMed, and the China National Knowledge Infrastructure (CNKI). Included studies were patients with POI diagnosed according to established international or Chinese guidelines. The intervention compared AS therapies (e.g., acupuncture, moxibustion, and electroacupuncture) with conventional treatments (oral herbs or hormone repl

SUBMITTER: Du Z 

PROVIDER: S-EPMC12313507 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature