Comparative effectiveness of traditional Chinese medicine injections combined with ACEI/ARB for diabetic nephropathy: A systematic review and network meta-analysis.

ABSTRACT:

Aim of the study

This systematic review and network meta-analysis aimed to evaluate the comparative effectiveness of traditional Chinese medicine injections (TCMIs) combined with angiotensin-converting enzyme inhibitors or angiotensin Ⅱ receptor blockers for diabetic nephropathy (DN).

Methods

Ten databases were searched. Primary endpoint indicators were urinary albumin excretion rate (UAER) and serum creatinine (Scr). Secondary endpoint indicators were blood urea nitrogen (BUN), urinary β₂-microglobulin, total cholesterol, triglyceride, systolic blood pressure, and total effective rate. Cochrane risk of bias tool (version 2.0) was used to evaluate the quality of the studies. The GRADE method was used to assess the whole network. Finally, Stata 16.0 software was us

SUBMITTER: Li A 

PROVIDER: S-EPMC12313559 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature