Application of magneto-luminescent gold nanoclusters with microfluidic systems to the determination analysis of tetracyclines.

ABSTRACT: A microfluidic analytical system based on magnetically retained nanomaterials has been developed using fluorometric detection. This system utilizes magnetic gold nanoclusters (AuMNCs) to determine total tetracyclines using three of them as model-chlortetracycline (CTC), doxycycline (DC), and oxytetracycline (OTC)-in water samples by monitoring the change in the luminescent signal produced upon interaction. AuMNCs were synthesized by adding preformed magnetic nanoparticles (MNPs) to bovine serum albumin (BSA) as stabilizer and ascorbic acid as a reducing agent. Their magnetic properties enable their retention in the reaction/detection zone of the microfluidic system. The reactor was integrated into the optical pathway of a conventional spectrofluorometer with a 3D-printed device to align th

SUBMITTER: Palma-Roldan J 

PROVIDER: S-EPMC12313782 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature