Sexual health in adult women with complete androgen insensitivity syndrome: a single centre cross-sectional study.

ABSTRACT:

Objective

We aimed to assess sexual health and body uneasiness in patients with complete androgen insensitivity syndrome (CAIS) using validated questionnaires, since literature is limited and heterogeneous.

Methods

Single-center, cross-sectional study on 34 adults with 46, XY karyotype and confirmed androgen receptor mutation (age = 34 ± 8.6 years), 29 gonadectomized and 5 with gonads in situ. All gonadectomized patients but 3 were receiving hormonal replacement therapy (HRT): 14 with transdermal oestradiol, 10 with oral oestradiol, 2 with testosterone. We measured hormonal levels and adherence to HRT, and we administered Female Sexual Function Index (FSFI), Female Sexual Distress Scale-Revised (FSDS-R) and Body Uneasiness Test (BUT) questionnaires.

Results

We registe

SUBMITTER: Mangone A 

PROVIDER: S-EPMC12313786 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature