Supplementary motor area enhanced hemodynamic responses to loading after inhibitory cTBS.

ABSTRACT: Large-extent movements (LEMs) are vital for daily activities, and their recovery remains a challenge in neurorehabilitation due to inevitable loading on muscles. Since inhibitory cTBS may facilitate recovery but also disrupt task control, we ask whether a previously identified linear relationship between load and cortical activation would retain, after cTBS over the contralateral supplementary motor area (SMA). It will set a benchmark for choosing resistance during brain stimulation. Hemodynamic activities of SMA and M1 during LEMs were monitored by functional Near-Infrared Spectroscopy (fNIRS) in this study. Twelve healthy participants received 40s of cTBS over SMA, before and after which the participants were instructed to complete LEMs with varying loads (0, 3, and 15 pounds) repetitive

SUBMITTER: Qiao Y 

PROVIDER: S-EPMC12313867 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature