Retrospective study of onychomycosis patients treated with ciclopirox 8% HPCH and oral antifungals applying artificial intelligence to electronic health records.

ABSTRACT: We conducted a multicenter retrospective analysis of 408 patients diagnosed with onychomycosis who attended three tertiary care Spanish hospitals. The study was conducted to assess the clinical characteristics and outcomes of onychomycosis patients undertaken combined treatment with ciclopirox 8% hydroxypropyl chitosan (CPX 8% HPCH) nail lacquer and oral antifungal agents (terbinafine, itraconazole, and fluconazole). Data were extracted and analyzed using the EHRead^® technology based on natural language processing and machine learning and using SNOMED CT terminology. The mean age was 51.1 years, with 54.4% females. Repeated nail trauma was the most common risk factor (7.1%). More than half of the patients (56.6%) underwent fungal culture. Terbinafine, itraconazole, and fluconazo

SUBMITTER: Roustan G 

PROVIDER: S-EPMC12313871 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature