Adverse childhood experiences impair cognitive function via social isolation and functional limitations in Chinese middle-aged and older adults.

ABSTRACT: Adverse childhood experiences (ACEs) are among the factors affecting cognitive function in middle-aged and older adults, but the combined effects of ACEs, social isolation and functional limitations on cognitive function have not been fully explored. This study used data from 6412 middle-aged and older adults from the 2018 China Health and Retirement Longitudinal Study (CHARLS) and the 2014 CHARLS Life Histories Survey. Mplus 8.0 software was used to construct a structural equation model with ACEs as the independent variable, cognitive function as the dependent variable, and social isolation and functional limitations as mediating variables. In this study, ACEs were positively associated with social isolation and functional limitations (r = 0.081, 0.070, P < 0.01) and negatively associated

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12314117 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature