Genomic insights into <i>Halorubrum ezzemoulense</i> strain TC23: Genetic basis for halophilic traits and biotechnological potential.

ABSTRACT: ObjectiveThis study aimed to explore the genomic features of Halorubrum ezzemoulense strain TC23, an extreme halophilic archaeon isolated from the Ayvalık Saltern in Türkiye, with a focus on its halophilic adaptations and potential biotechnological applications.MethodsWhole-genome sequencing was performed using the Illumina NovaSeq 6000 platform. In silico analyses were conducted using tools such as Prokka and eggNOG-mapper for structural and functional annotation, including gene ontology (GO), Clusters of Orthologous Groups (COG), and Kyoto Encyclopedia of Genes and Genomes pathway predictions. Taxonomic validation was performed with TYGS, and the genome was compared to related strains using digital DNA-DNA hybridization (dDDH), average nucleotide ıdentity, and phylogenomic tree co

SUBMITTER: Kesbic FI 

PROVIDER: S-EPMC12314224 | biostudies-literature | 2025 Jul-Sep

REPOSITORIES: biostudies-literature