Interventions to Reduce the Risk of Hypocalcemia After Parathyroidectomy for People With Advanced Chronic Kidney Disease: A Systematic Review.

ABSTRACT:

Background

People with advanced chronic kidney disease (CKD) and secondary hyperparathyroidism (sHPT) refractory to medical therapy often require surgical parathyroidectomy. Severe and prolonged hypocalcemia immediately following parathyroidectomy for sHPT is often termed "hungry bone syndrome" (HBS).

Objective

To systematically review the effect of pre-operative interventions on post-operative hypocalcemia, HBS, and other related outcomes in patients with CKD and sHPT undergoing parathyroidectomy.

Design

This is a systematic review study.

Setting

Diverse study designs conducted in any country.

Patients

Adult patients with CKD complicated by sHPT undergoing parathyroidectomy.

Measurements

Post-operative hypocalcemia, HBS, symptomatic hypocalcemia,

SUBMITTER: Landsberg A 

PROVIDER: S-EPMC12314243 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature