Longitudinal patterns of fluid overload, blood volume and vascular refilling: a prospective study in patients on maintenance hemodialysis.

ABSTRACT:

Introduction

Patients on maintenance hemodialysis accumulate excess fluid between treatments. Intradialytic removal of fluid via ultrafiltration is partly compensated by vascular refilling from the interstitial space. Associations between whole-body fluid status and blood volume were previously investigated on the population level. The aim of this observational cohort study was to assess longitudinal changes in fluid compartment volumes on an intra-patient level.

Methodology

Pre-dialysis bioimpedance spectroscopy measurements and absolute blood volume estimations were conducted in maintenance hemodialysis patients during 14 consecutive dialysis treatments over 5 weeks. Blood volume was determined using the dialysate bolus method. Longitudinal changes were evaluated using lin

SUBMITTER: Mussnig S 

PROVIDER: S-EPMC12314271 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature