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Diagnostic Risk Prediction Models for Upper Gastrointestinal Cancers: A Systematic Review.


ABSTRACT: Upper gastrointestinal (UGI) cancers are often detected late. Risk prediction models could facilitate earlier detection by identifying patients at risk for further investigation. We systematically reviewed evidence on UGI diagnostic risk prediction models. A search of MEDLINE, Embase, and CENTRAL was conducted for studies reporting on the development and/or validation of diagnostic risk prediction models for UGI cancers (pancreatic, gastric, esophageal, gallbladder, and/or biliary tract). Studies had to report at least one quantitative measure of model performance to be eligible for inclusion. A total of 82 studies describing 162 UGI risk models were included. Models predicted gallbladder (n = 6), gastric (n = 25), esophageal (n = 34), gastroesophageal (n = 14), and pancreatic (n = 83) can

SUBMITTER: Saunders TS 

PROVIDER: S-EPMC12314510 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature