Percutaneous transhepatic cholangiography and drainage for biliary strictures after pediatric liver transplantation.

ABSTRACT:

Objectives

Biliary strictures (BS) remain frequent after pediatric liver transplantation (pLT) and best management practices are still lacking. This study systematically assesses efficacy of stricture treatment by percutaneous transhepatic cholangiography and drainage (PTCD).

Methods

Online databases were searched for studies on PTCD treatment of BS after pLT from the year 2000 to 2024. Efficacy and safety profile of PTCD were analyzed. Influence of various risk factors on outcome parameters was compared by meta-regression.

Results

Twenty-seven observational studies with 802 patients undergoing PTCD for BS met the inclusion criteria. Incidence of BS was 13.1% (95% confidence interval [CI]: 10.3-16.1) in 6543 patients reported who underwent pLT between 1989 and 2020. O

SUBMITTER: Seisenbacher J 

PROVIDER: S-EPMC12314590 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature