Construction and Implications of Nomogram for Predicting Sustained Glycemic Remission After Short-Term Intensive Insulin Therapy in Newly Diagnosed Type 2 Diabetes.

ABSTRACT:

Background

Early short-term intensive insulin therapy may induce sustained glycemic remission in type 2 diabetes. However, patients' responses vary greatly. Exploring key factors to improve glycemic control and predict the probability of remission precisely is meaningful for future treatment.

Methods

Patients with newly diagnosed type 2 diabetes receiving 2-3 weeks of intensive insulin therapy were followed up for at least 1 year in three randomized clinical trials. Data of theirs were extracted with the same inclusion criteria and divided into training and validation sets. A nomogram was constructed in the training set and tested in the internal validation set.

Results

Among 302 patients with transient intensive insulin therapy, 162 (53.64%) patients achieved the 1-y

SUBMITTER: Xu L 

PROVIDER: S-EPMC12314641 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature