Drug treatment strategies for erosive esophagitis in adults: a narrative review.

ABSTRACT:

Background and objective

Erosive esophagitis (EE) is the second most common phenotype of gastroesophageal reflux disease (GERD). While proton pump inhibitors (PPIs) are considered the mainstay treatment for healing and maintaining remission of EE, a significant proportion of patients, particularly those with advanced grades, fail to respond adequately. This review provides an updated overview of the current pharmacological treatment options for EE.

Methods

An extensive electronic literature search was performed using PubMed database to identify relevant articles. The search included prospective clinical trials, observational trials, case-control studies, systematic reviews with or without meta-analysis, and narrative reviews describing pharmacological therapy for adult patie

SUBMITTER: Shibli F 

PROVIDER: S-EPMC12314673 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature