Importance of allergic sensitisation for normal range of fractional exhaled nitric oxide in adolescents.

ABSTRACT:

Background

In addition to body anthropometrics, allergen sensitization has been shown to influence the levels of exhaled fractional nitric oxide (FeNO) in adults, but whether this relationship is valid also in younger age groups, how it compares to the fixed cut-off levels recommended for clinical practice, and relates to respiratory symptoms remains to be confirmed.

Method

FeNO, sensitization, respiratory symptoms, and spirometry were evaluated in 2054 adolescents taking part in the 16-year follow-up of the Swedish BAMSE birth cohort.

Results

The median and upper limit of FeNO was related to the presence and type of allergic sensitisation and poorly represented by one fixed cutoff. For example, the 95th percentiles for sensitisation to dogs were 89 ppb in females and

SUBMITTER: Hallberg J 

PROVIDER: S-EPMC12314734 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature