Infections do not play fair: the Charlson-Age Comorbidity Index reveals sex-specific risk in laparotomy patients in an LMIC.

ABSTRACT:

Background

Surgical site infections (SSIs) are a major cause of increased morbidity, hospital stay, care costs, and mortality in surgical patients; these can be prognosticated by the Charlson Comorbidity Index (CCI) and accounting for age-the Charlson-Age Comorbidity Index (CACI). Given the limited use of CCI/CACI in low- and middle-income countries, we aimed to assess the use of CCI/CACI in prognosticating the 30-day incidence of SSIs among exploratory laparotomy patients at a tertiary care center in Pakistan.

Methods

The study analyzed data from adult patients with International Classification of Diseases-9 CM primary index procedure codes for exploratory laparotomy at a tertiary teaching hospital between 2010 and 2019. The primary exposure was categorized into mild (score

SUBMITTER: Abdul Rahim K 

PROVIDER: S-EPMC12314809 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature