Magnetic resonance imaging characteristics of small cell and non-small cell lung cancer brain metastases: a retrospective study.

ABSTRACT: Brain metastases (BMs) from bronchopulmonary tumors are a major cause of morbidity and mortality and significantly reduce the quality of life in oncology patients. Their treatment depends on imaging features (size, number, location) and their genetic mutation subtype, small-cell lung cancer (SCLC) or non-small cell lung cancer (NSCLC). In patients with SCLC, prophylactic whole-brain radiotherapy (WBRT) with hippocampal sparing (HS) is recommended, whereas in patients with NSCLC, systemic targeted therapy is preferred. Multiple studies have analyzed the MRI morphology of BMs from both SCLC and NSCLC to identify specific imaging characteristics that can guide the selection of appropriate treatment. However, data on lung cancer (LC) brain metastases in patients from Romania are scarce or none

SUBMITTER: Pomohaci D 

PROVIDER: S-EPMC12314843 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature