Combining mpox vaccination and behavioural changes to control possible future mpox resurgence among men who have sex with men: a mathematical modelling study.

ABSTRACT:

Introduction

The 2022 outbreak of mpox subclade IIb in the Netherlands affected primarily men who have sex with men (MSM). Despite the sharp decline in cases, concerns remain about future mpox outbreaks. This study investigated the effect of mpox introductions, accounting for vaccination, behavioural changes and introductions of subclades with different characteristics.

Methods

This study developed a compartmental model for mpox among MSM. Three levels of sexual activity were distinguished: low, medium and high. The group with high activity accounted for 5% of the population with the highest numbers of sexual partners, and the group with low activity included 60% with the lowest numbers of partners. In the model, individuals were allowed to change sexual activity level. Seve

SUBMITTER: Xiridou M 

PROVIDER: S-EPMC12315014 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature