Threshold-based compliance with diabetic ketoacidosis management protocols and its association with inpatient mortality: a retrospective single-centre study in a tertiary hospital in Karachi, Pakistan.

ABSTRACT:

Objectives

The aim of this study was to evaluate protocol adherence and its impact on inpatient mortality in patients with diabetic ketoacidosis (DKA) at a tertiary hospital in Karachi. The major hypothesis was that adherence to the DKA protocol reduces inpatient mortality.

Design

This was a retrospective cohort study.

Setting

The study was conducted at the Aga Khan University Hospital (AKUH), Karachi, a tertiary care hospital in Pakistan.

Participants

The study included patients diagnosed with DKA and admitted to AKUH from 2017 to 2021. Eligibility criteria included patients aged 18 and older, excluding those with incomplete records or referred to other hospitals.

Primary and secondary outcome measures

The primary outcome was inpatient mortality. The an

SUBMITTER: Fatima S 

PROVIDER: S-EPMC12315034 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature