Effectiveness of switching to doravirine-based antiretroviral therapy: A real-world study in Germany.

ABSTRACT:

Objectives

Doravirine (DOR)-based antiretroviral therapy (ART) has been shown in clinical trials to be effective and well tolerated in treating HIV-1. The EffectiVeness of SwItChing to DORavirine-based Antiretroviral Therapy (VICDOR) study characterized the use, effectiveness and impact on body weight and lipids of DOR-based ART in a virologically suppressed switch population using real-world data from Germany.

Methods

VICDOR was a multicentre, retrospective chart review study of virologically suppressed adults with HIV in Germany who switched to DOR-based ART between January 2019 and February 2021. Demographic, clinical and laboratory data were collected up to 15 months after the switch.

Results

A total of 193 individuals were included, with a median age of 49 years

SUBMITTER: Wyen C 

PROVIDER: S-EPMC12315075 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature