Patient-centred estimation of multimorbidity in chronic disease populations: a novel approach integrating global burden of disease metrics and healthcare administrative data.

ABSTRACT:

Background

Although chronic diseases represent a growing global health priority, significant gaps remain in understanding the burden of multimorbidity. This study developed an original methodology to estimate the burden of thirty major chronic diseases at the individual patient level, in terms of Disability-Adjusted Life years (DALYs), Years Lived with Disability (YLD), and Years of Life Lost due to premature death (YLL).

Methods

The Disability weights (DWs) estimated by the Global Burden of Disease (GBD) study were integrated with information from healthcare databases. A panel of medical specialists established the criteria for assigning the level of severity, and thus a specific DW, to each chronic disease. The patient-centred YLD metric was estimated as the cumulative of

SUBMITTER: Fortuna D 

PROVIDER: S-EPMC12315285 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature