Optimal mean arterial pressure for favorable neurological outcomes in patients after cardiac arrest.

ABSTRACT:

Background

Optimal mean arterial pressure (MAP) range after cardiac arrest remains uncertain. This study aimed to investigate the association between MAP and neurological outcomes during the early post-resuscitation period, with the goal of identifying optimal MAP range associated with favorable outcomes.

Methods

This retrospective observational study included 291 post-cardiac arrest patients treated at a tertiary care center. Five machine learning models to predict favorable neurological outcomes using hourly MAP measurements during the first 24 h after return of spontaneous circulation (ROSC) were compared and Random Forest model was selected due to its superior performance. Variable importance and Shapley Additive exPlanations (SHAP) were used to investigate the associati

SUBMITTER: Lee S 

PROVIDER: S-EPMC12315296 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature