METS-VF as a novel predictor of gallstones in U.S. adults: a cross-sectional analysis (NHANES 2017-2020).

ABSTRACT:

Background and aims

Obesity is a well-established risk factor for gallstone formation, but traditional anthropometric measures (e.g., BMI, waist circumference) inadequately assess metabolically active visceral adiposity. The novel Metabolic Score for Visceral Fat (METS-VF) may better capture obesity-related metabolic dysfunction. We aimed to investigate the association between METS-VF and gallstone prevalence and compare its predictive performance against conventional obesity indices (WC, LAP, VAI) in a U.S. national cohort.

Methods

This cross-sectional study analyzed nationally representative data from 3,010 US adults in NHANES 2017-2020 (aged 20-85 years, 51.3% male, multi-ethnic population). We employed weighted multivariable logistic regression to examine the METS-VF-gal

SUBMITTER: Wang H 

PROVIDER: S-EPMC12315333 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature