Cognitive change 5+ years since the onset of a psychotic disorder: A systematic review and meta-analysis.

ABSTRACT: Cognitive impairments are a core feature of psychotic disorders, but their long-term trajectory remains contentious. Previous meta-analyses focused on the first 5 years following psychosis onset. Here, we evaluated the change in cognitive impairments in psychotic disorders with a meta-analysis of studies with follow-ups of 5+ years. Following preregistration, databases were searched for relevant articles until July 2024. Two authors screened the reports for studies reporting on the change in cognitive impairments in global cognition, verbal learning and memory, visual learning and memory, working memory, attention, speed of processing, reasoning and problem-solving, and verbal fluency in individuals with psychotic disorders, with a minimum follow-up of 5 years. Three authors extracted data

SUBMITTER: Ghanem J 

PROVIDER: S-EPMC12315663 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature