Epidemiological characteristics of invasive meningococcal disease and carriage prevalence of <i>Neisseria meningitidis</i> in the Xinjiang Uygur Autonomous Region, China, 2004-2023: a retrospective study.

ABSTRACT:

Objective

The Xinjiang Uygur Autonomous Region (Xinjiang) currently exhibits the high incidence rates of invasive meningococcal disease (IMD) in China. Current epidemiological data on meningococcal carriage rates among asymptomatic individuals remain sparse, with limited population-based studies systematically investigating the prevalence of Neisseria meningitidis colonization in the general population. This study employs a dual-pronged epidemiological approach to systematically characterize the clinical-epidemiological profile of IMD in Xinjiang and quantify the nasopharyngeal carriage prevalence of N. meningitidis among asymptomatic populations, while identifying region-specific sociodemographic and behavioral determinants of carriage dynamics.

Methods

Epidem

SUBMITTER: Nazhaerbieke H 

PROVIDER: S-EPMC12315827 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature