Evaluation of race-free eGFR equations in individuals of different ethnicity.

ABSTRACT:

Background

Glomerular filtration rate (eGFR) derived from serum creatinine (eGFR_cr), cystatin C (eGFR_cys), or both (eGFR_cr-cys) by race-free equations are recommended staging chronic kidney disease (CKD). The current study aimed to compare these race-free eGFR equations for screening for low-grade CKD in Blacks and non-Blacks and to evaluate their association with mortality.

Methods

Race-free eGFR equations were evaluated in four studies with specific inclusion criteria based on the original research goals: African-PREDICT (341/380 healthy Black/White South Africans), FLEMENGHO (709 White community-dwelling Flemish), NHANES (1760/7931 Black and non-Black adult Americans), and 401 Black African patients hospitalised in Mbuji Mayi, Democratic R

SUBMITTER: An DW 

PROVIDER: S-EPMC12315838 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature